T7660

Sigma

 

Tetracycline hydrochloride

powder, cell culture tested

CAS Number:64-75-5
Linear Formula:C22H24N2O8 · HCl
Molecular Weight:480.90
Beilstein Registry Number:3844873
EC Number:200-593-8
MDL number:MFCD00078142
PubChem Substance ID:24900468

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Description

ApplicationRecommended for use in cell culture applications at 10 mg/L.
Biochem/physiol ActionsMode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Loss of cell wall permeability.

Properties

formpowder
mp220-223 °C(lit.)
solubilityH2O: 10 mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days.
suitabilitycell culture tested
storage temp.−20°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-36
WGK Germany2
RTECSQI9100000

References

MerckMerck 13,9271
BeilsteinBeil. 14,IV,2627
referenceAldrich MSDS 1, 1654:B / Corp MSDS 1 (2), 3252:B / FT-IR 1 (2), 421:C / FT-IR 2 (2), 3103:A / RegBook 1 (2), 2097:M / Sax 6, 2521 / Sigma FT-IR 1 (1), 720:D / Structure Index 1, 332:C:1